Dietary oils modify lipid molecules and nutritional value of fillet in Nile tilapia: A deep lipidomics analysis☆

學生姓名: 李玗庭
學期: 107下
摘  要: The nutritional value of fish fillet can be largely affected by dietary oils. However, little is known about how
dietary oils modify lipid molecules in fish fillets. Through biochemical and lipidomics assays, this study demonstrated
the molecular characteristics of fillet lipids in Nile tilapia fed with different oils for six weeks. High
18:2n-6 and low 18:3n-3 deposition in phosphoglycerides resulted high 18:2n-6/18:3n-3 ratio in tilapia. Dietary
n-3 VLCUFAs intake increased its deposition at sn-1/3 of triglycerides and at sn-2 of phosphatidylcholines.
Irrespective of dietary oil, 16:0 was distributed preferentially at the outer positions of glycerol backbone. High
18:2n-6 accumulated at sn-2 position for fish fed with n-3 PUFA-enriched oils. High 18:3n-3 deposited at sn-1/3
in TG, sn-1 in phosphatidylethanolamines, while at sn-2 in phosphatidylcholines. Together, dietary oils change
the composition and positional distribution of fatty acids on the glycerol backbone, and change nutritional value
of fish for human health.