學生姓名:
曾揚捷
指導教授:
江孟燦
學期:
107下
摘 要:
PCL with biodegradable property and Spirulina with various biological activities offer good alternative
ingredients for the fabrication of functional nanofibers in tissue engineering. The aim of the study is to obtain
PCL/Spirulina nanofibers with low diameters and to determine their wettability, antioxidant activity, and
phycocyanin release to evaluate their potential as bioactive scaffolds in different applications. PCL/acetic
acid/pyridine solutions with three different Spirulina concentrations were electrospun and the obtained
nanofibers were investigated. The thinnest PCL/Spirulina nanofibers (117.20 nm) were obtained at 1.5%
Spirulina concentration. Although PCL nanofibers with 6% Spirulina concentration showed the highest
antioxidant activity and amount of phycocyanin released, PCL nanofibers with 3% Spirulina concentration
having similar in vitro results showed superiority when considering the diameter and uniformity of the
nanofibers and the cost of the material. The PCL/Spirulina nanofibers with small diameters and antioxidant
activity could be regarded as potential extracellular matrix material for tissue engineering.
2017-Assessment_of_antioxidant_activity_and_phycocyanin_release_of_Spirulina_loaded_poly(εcaprolactone)_electrospun_nanofibers.pdf