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yes2023年已發表相關研究:

2023年本實驗室共發表17篇第一或通訊作者的SCI文章(7篇為112年度國科會計畫經費補助),其內容都以微生物燃料電池篩選中草藥抗病毒的活性和中草藥藥理活性為主軸,包含中藥複方(淨冠方、金耆飲)篩選抗病毒和免疫調節,炮製陳皮、炮製陳皮提升微生物燃料電池的功率密度,以及芝麻、桂花、紫蘇藥理活性篩選等研究內容:

  1. 微生物燃料電池篩選中藥複方抗COVID-19和免疫調節,針對防疫用藥淨冠方和防疫保健食品金耆飲評估微生物燃料電池PD功率密度和指標成分對COVID-19H1N1和免疫調節分子對接的關聯性。
  • Christine Joyce F. Rejano, Bor-Yann Chen, Gilbert S. Sobremisana, Lemmuel L. Tayo, Kun-Teng Wang, Po-Wei Tsai* (2023, Oct). Electrochemical analysis via microbial fuel cells reveals electron-stimulating characteristics, immunomodulation and antiviral properties of Ji Qin Yin. Journal of the Taiwan Institute of Chemical Engineers, 152, 105193. nstc 112-2221-E-309-001.
  • Po-Wei Tsai, Ryan Christian Mailem, Lemmuel L. Tayo, Chung-Chuan Hsueh, Chi-Chun Tseng, Bor-Yann Chen (2023, May). Interactive network pharmacology and electrochemical analysis reveals electron transport-mediating characteristics of Chinese medicine formula Jing Guan Fang. Journal of the Taiwan Institute of Chemical Engineers, 147, 104898.

  1. 微生物燃料電池篩選抗COVID-19候選中藥藥物2022年本人首度發表微生物燃料電池與抗COVID-19之文章,衍生至今2023年,篩選由台灣中藥典收錄三種品種(R. officinale (RO), R. palmatum (RP), and R. tanguticum (RT))藥用大黃以RO水萃物具有最佳MFCs功率密度,RT產電效能最差,經由10種傳統炮製方法,成功找出醋製大黃可以提升MFCs功率密度,經由抗病毒分子對接評估,找出其指標成分rhein大黃酸具有抗登革熱、日本腦炎、C肝的活性,同時也是SARS-CoV-2 RdRp inhibitor。同時也完成112年度國科會計畫炮製陳皮和菲律賓金桔的能量轉換與抗病毒活性評估,比較紫蘇、紅紫蘇、魚腥草微生物燃料電池篩選抗病毒活性之主成分迷迭香酸(紫蘇)quercitrin (魚腥草),共七篇期刊產出。
  • Po-Wei Tsai, Bor-Yann Chen, Ling-Ling Yang (2023, Sep). Interactive Deciphering Electron-mediating Characteristics of Rheum species and Potential Bioenergy-Steered Anti-COVID-19 RdRp Inhibitor. Journal of the Taiwan Institute of Chemical Engineers, 151, 105124.
  • Po-Wei Tsai, Cheng-Yang Hsieh, Jasmine U. Ting, Kristian Gil G. Rogio, Chia- Jung Lee, Kathlia A. De Castro-Cruz, Yi-Ru Ciou, Tzu-Kuan Lien, Ling-Ling Yang, Chung-Chuan Hsueh, Bor-Yann Chen (2023, Feb). Unraveling the bioenergy production and electron transport characteristics of processed Rheum palmatum L. for antiviral drug development. Industrial Crops & Products, 195, 116488.
  • Po-Wei Tsai, Kristian Gil G. Rogio, Cheng-Yang Hsieh, Kathlia A. De Castro Cruz, Chia-Jung Lee, Chung-Chuan Hsueh, Ting-Ning Huang, Wei-Zhun Lu, Zong-Lin Xie, Yong-Ni Jhen, Bor-Yann Chen (2023, Feb). Optimal stimulation of Citrus reticulate for bioenergy extraction in MFCs and antioxidant activity via traditional Chinese medicine processing methods. Journal of the Taiwan Institute of Chemical Engineers, 143, 104690.
  • Po-Wei Tsai, Timothy Jen R. Roxas, Lemmuel L. Tayo, Yi-Ru Lin, Chung-Chuan Hsueh, Bor-Yann Chen (2023, Apr). Unveiling bioenergy-stimulating and electron-transporting characteristics of metabolites from Citrus microcarpa peels and pulps as medicated diet of sustainable energy resource. Biochemical Engineering Journal, 196, 108951.
  • Po-Wei Tsai, Maria Regina Gean G. Aledia, Kathlia A. De Castro-Cruz, Patrick Jay B. Garcia, Cheng-Jui Shen, Chung-Chuan Hsueh, Chung-Yu Chen, Bor-Yann Chen (2023, Jun). Exploring promising electron-shuttling characteristics of Perilla frutescens and potential anti-viral activity via bio-energy generation in microbial fuel cells. Sustainable Chemistry and Pharmacy, 34, 101141.
  • Maria Regina Gean G. Aledia#, Po-Wei Tsai#, Kathlia A. De Castro-Cruz, Cheng-Jui Shen, Chung-Chuan Hsueh, Bor-Yann Chen (2023, May). Unveiling electron-mediating properties of red perilla (shiso) leaves for bioenergy-steered antiviral capabilities. Biochemical Engineering Journal, 197, 108986.
  • Chia-Kai Lin, Bor-Yann Chen, Jasmine U. Ting, Kristian Gil G. Rogio, Po-Wei Tsai*, Yung-Chuan Liu* (2023, Apr). Deciphering Houttuynia cordata extract as electron shuttles with anti-COVID-19 activity and its performance in microbial fuel cells. Journal of the Taiwan Institute of Chemical Engineers, 145, 104838.

  1. 分子對接評估天然物藥理活性,延伸先前MFC篩選大黃、咖啡葉和淨冠方(提供能量轉換的主藥材厚朴) 主題,以分子對接篩選抗帕金森氏症主成分的研究評估,找出具有抗帕金森氏症潛力的活性成分,分別是咖啡葉中caffeine, catechin, chlorogenic acid和厚朴magnatriol B, obovatol, randaiol,而大黃具有神經保護的作用。另外也發表葫蘆樹果實 (Crescentia cujete)分子對接篩選抗發炎和抗氧化的活性成分naringenin, pinocembrin, eriodictyol
  • Garcia, P.J.B.; Huang, S.K.-H.; De Castro-Cruz, K.A.; Leron, R.B.; Tsai, P.-W.* (2023, Sep). In Silico Neuroprotective Effects of Specific Rheum palmatum Metabolites on Parkinson’s Disease Targets. Int. J. Mol. Sci., 24(18), 13929.
  • Christine Joyce F. Rejano, Lemmuel L. Tayo, Bor-Yann Chen, Po-Wei Tsai* (2023, Sep). In Silico Investigation of Identified Major Metabolites from Coffea arabica Leaves Against Parkinson’s Disease Target Proteins for Neuroprotective Drug Development. Letters in Drug Design & Discovery. (Accepted).
  • Zaina Allyson Rivera, Lemmuel Tayo, Bor-Yann Chen, Po-Wei Tsai* (2023, Aug). In Silico Evaluation of the Feasibility of Magnolia officinalis ElectronShuttling Compounds as Parkinson’s Disease Remedy. Letters in Drug Design & Discovery. (Accepted).
  • Alecsanndra L. Gonzales, Steven Kuan-Hua Huang, Ureah Thea A. Sevilla, Cheng-Yang Hsieh, Po-Wei Tsai* (2023, Apr). In Silico Analysis of Anti-Inflammatory and Antioxidant Properties of Bioactive Compounds from Crescentia cujete L.. Molecules, 28(8), 3547.

  1. 芝麻、桂花、紫蘇藥理活性,評估芝麻主成分sesamin降血糖、抗發炎、抗退化性關節炎和抗COVID-19活性,桂花和紫蘇主成分rutin和迷迭香酸具有抗攝護腺癌的活性。

  • Shu-Ming Huang, Cheng-Hung Chuang, Christine Joyce F. Rejano, Lemmuel L. Tayo, Cheng-Yang Hsieh, Steven Kuan-Hua Huang*, and Po-Wei Tsai* (2023, Oct). Sesamin: A Promising Therapeutic Agent for Ameliorating Symptoms of Diabetes. Molecules, 28(21), 7255.
  • Shu-Ming Huang, Cheng-Yang Hsieh, Jasmine U. Ting, Kathlia A. De Castro-Cruz, Ching-Chiung Wang, Chia-Jung Lee*, Po-Wei Tsai* (2023, Sep). Anti-COVID-19, Anti-Inflammatory and Anti-Osteoarthritis Activities of Sesamin from Sesamum indicum L.. Bioengineering, 10, 1263.
  • Huang, S.K.-H.; Bueno, P.R.P.; Garcia, P.J.B.; Lee, M.-J.; De Castro-Cruz, K.A.; Leron, R.B.; Tsai, P.-W. * (2023, Sep). Antioxidant, Anti-Inflammatory and Antiproliferative Effects of Osmanthus fragrans (Thunb.) Lour. Flower Extracts. Plants, 12, 3168.
  • Patrick Jay B. Garcia, Steven Kuan-Hua Huang, Kathlia A. De Castro-Cruz, Rhoda B. Leron, Po-Wei Tsai* (2023, Aug). An in vitro evaluation and network pharmacology analysis of prospective anti-prostate cancer activity from Perilla frutescens. Plants, 12, 3006.