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TSAI, MIN-LANG

Professor

Education：Ph.D. of National Taiwan Ocean Univ., Taiwan
  Specialty：Biopolymer, Food Processing, Rheology
        Office：Food Science Building Room 108           
            Lab：Food Science Building Room 106 
           TEL：+886-2-24622192 Ext.5122
       E-mail：tml@mail.ntou.edu.tw

Education

  • 1997 / Ph.D. / Department of Food Science, National Taiwan Ocean University
  • 1993 / M.S.  / Department of Food Science, National Taiwan Ocean University
  • 1991 / B.S.   / Department of Food and Nutrition, Chinese Culture University


Research Area

  1. Application of porous technology, including explosive expansion, microwave expansion, freeze-thaw cycle, solvent swelling)
  2. Green production process of chitin and chitosan (physical pretreatment/microorganisms, enzymes, and/or green solvents)
  3. Novel chitin green solvent system
  4. Smart packaging materials (edible, detectable, displayable, antibacterial, antioxidant)
  5. Application of biopolymers in biomedicine (β-glucan particles, chitin, chitosan, fucoidan, gelatin, nanoparticles, hydrogels, scaffolds, etc.)


Refereed Papers (Last 5 years)

  1. Lu, H. T., Wang, Y. J., Lin, C., Hsu, F. Y., Tsai, M. L.,* & Mi, F. L.* (2023). Sequential deacetylation/self-gelling chitin hydrogels and scaffolds functionalized with fucoidan for enhanced BMP-2 loading and sustained release. Carbohydrate Polymers, 315, 121002.
  2. Huang, H. L., Tsai, I. L., Lin, C., Hang, Y. H., Ho, Y. C., Tsai, M. L.,* & Mi, F. L.* (2023). Intelligent films of marine polysaccharides and purple cauliflower extract for food packaging and spoilage monitoring. Carbohydrate Polymers, 299, 120133.
  3. Chen, S. K., Goh, W. N., Tsai, M. L.,* Wang, S. T.,* & Wu, J. Y.* (2022). Novel applications of puffing gun in foods. Journal of the Fisheries Society of Taiwan, 49(2), 59-69.
  4. Wu, J. Y.,* & Tsai, M. L.* (2022). Mini review: Ratiometric fluorescent and carbon dots based application for sea food and water safety sensing. Journal of the Fisheries Society of Taiwan, 2022, 49(2), 105-111.
  5. Wang, S. T., Lu, Y. Y., & Tsai, M. L.* (2021). Formulation and evaluation of chitosan/NaCl/maltodextrin microparticles as a saltiness enhancer: Study on the optimization of excipients for the spray-drying process. Polymers, 13(24), 4302.
  6. Wu, L. T., Tsai, I. L., Ho, Y. C., Hang, Y. H., Lin, C., Tsai, M. L.,* & Mi, F. L.* (2021). Active and intelligent gellan gum-based packaging films for controlling anthocyanins release and monitoring food freshness. Carbohydrate Polymers, 254, 117410.
  7. Cheng, T. M., Li, R., Kao, Y. C. J., Hsu, C. H., Chu, H. L., Lu, K. Y., Changou, C. A., Chang, C. C., Chang, L. H., Tsai, M. L.,* & Mi, F. L.* (2020). Synthesis and characterization of Gd-DTPA/fucoidan/peptide complex nanoparticle and in vitro magnetic resonance imaging of inflamed endothelial cells. Materials Science & Engineering C, 114, 111064.
  8. Chou, C. M., Mi, F. L., Horng, J. L., Lin, L. Y., Tsai, M. L., Liu, C. L., Lu, K. Y., Chu, C. Y., Chen, Y. T., Lee, Y. L. A., & Cheng, C. H.* (2020). Characterization and toxicology evaluation of low molecular weight chitosan on zebrafish. Carbohydrate Polymers, 240, 116164.
  9. Yang, Y. N., Lu, K. Y., Wang, P., Ho, Y. C., Tsai, M. L.,* & Mi, F. L.* (2020). Development of bacterial cellulose/chitin multi-nanofibers based smart films containing natural active microspheres and nanoparticles formed in situ. Carbohydrate Polymers, 228, 115370.
  10. Lu, Y. Y., Wang, S. T.,* Shih, M. C., & Tsai, M. L.* (2019). Chitosan/NaCl microparticles used as sodium reduction strategy: Studies on the physicochemical characteristics and optimization of preparation conditions. Journal of the Fisheries Society of Taiwan, 46(1), 65-77.
  11. Lu, H. T.,* Chang, W. T., Tsai, M. L., Chen, C. H., Chen, W. Y., & Mi, F. L.* (2019). Development of injectable fucoidan and biological macromolecules hybrid hydrogels for intra-articular delivery of platelet-rich plasma. Marine Drugs, 17, 236.
  12. Tsai, W. C., Wang, S. T., Chang, K. L. B., & Tsai, M. L.* (2019). Enhancing saltiness perception using chitin nanomaterials. Polymers, 11, 719.
  13. Lu, K. Y., Lin, Y. C., Lu, H. T., Ho, Y. C., Weng, S. C., Tsai, M. L.,* & Mi, F. L.* (2019). A novel injectable in situ forming gel based on carboxymethyl hexanoyl chitosan/hyaluronic acid polymer blending for sustained release of berberine. Carbohydrate Polymers, 206, 664-673.
  14. Chang, F. S., Chin, H. Y., & Tsai, M. L.* (2018). Preparation of chitin with puffing pretreatment. Research on Chemical Intermediates, 44, 4939-4955.
  15. Tsai, L. C., Tsai, M. L., Lu, K. Y., & Mi, F. L.* (2018). Synthesis and evaluation of antibacterial and anti-oxidant activity of small molecular chitosan–fucoidan conjugate nanoparticles. Research on Chemical Intermediates, 44, 4855-4871.
  16. Tsai, Y. H., Yang, Y. N., Ho, Y. C., Tsai, M. L.,* & Mi, F. L.* (2018). Drug release and antioxidant/antibacterial activities of silymarin-zein nanoparticle/bacterial cellulose nanofiber composite films. Carbohydrate Polymers, 180, 286–296.
     

Book Chapter

  1. Wang, S. T., Tsai, C. C., Shih, M. C.,* & Tsai, M. L.* (2021). Flavor-related applications of chitin and chitosan in foods: Effect of structure and properties on the efficacy. In: Jayakumar, R., Prabaharan, M. (eds) Chitosan for Biomaterials III. Advances in Polymer Science, 287, 169-202. Springer, Cham, Switzerland.
  2. Tsai, M. L. and Chen, R. H. (2016). Modifying the molecular weight of chitosan. In: J. A. Jennings and J. D. Bumgardner (eds) Chitosan-based biomaterials, Vol I: Fundamentals. Woodhead Publishing, Sawston, England.

Patent

  1. Method of chitin deacetylation. Republic of China Patent I443110; People's Republic of China Patent CN 103145873B; Vietnam Patent 20364
  2. Method of preparing chitin nanofibers. Republic of China Patent I516502; United States Patent. US 9,644,084B2
  3. Method of pretreating crab or shrimp shells and method of preparing α-chitin. Republic of China Patent I567089
  4. Method for manufacturing formulated salt. Republic of China Patent I565659
  5. Method for manufacturing chitin nanofibers-sodium chloride solution. Republic of China Patent I631905
  6. Method for manufacturing chitin aqueous solutions. Republic of China Patent I740312