The effect of coix seed on whitening and anti-aging by cell model
學生姓名:
唐碩亨
指導教授:
陳建利
學 期:
111下
摘 要:
The methanolic extract had the highest concentrations of flavonoids and coixol. The ethanolic extract at 1 mg/mL inhibited tyrosinase activity in B16F10 melanocytes by 48.4% and fragments 369–377 of human tyrosinase (hTyr) by 50.7%. The human skin fibroblasts (HSF) is treated with CLRF (Coix seed Lactobacillus reuteri fermented extract), cell viability, total antioxidant capacity, superoxide dismutase (SOD) activity, catalase (CAT) activity, collagen type I (COL-I) content, and synthesis of hyaluronic acid (HA) are significantly increased, and reactive oxygen species (ROS) and matrix metalloproteinase-1 (MMP-1) content are decreased, effectively protecting skin structure. In conclision, coix seed can be used to skin whitening and anti-aging cosmetics, but still need more experiments to prove.
摘要.pdf